Advances in Research and Applications by Robert S.; Thimann, Kenneth V.; Marrian, G. F. Harris PDF

By Robert S.; Thimann, Kenneth V.; Marrian, G. F. Harris

ISBN-10: 0127098100

ISBN-13: 9780127098104

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Historical Burning sensations or shooting pains in the feet have long been recognized as adisorder occurring in tropical countries. Bontius in 1645, in his description of beriberi, refers to radiating pains in the soles of the feet which “attack those who unwarily sleep exposed to the land-winds which DIETARY NEUROPATHIES 19 issue every morning about sunrise from the neighbouring mountains, suddenly seizing them with a painful sensation in the periosteum of the arms and legs. In some persons the pain abates as the day advances and the air becomes warmer: but in others it continues for a considerable time, attended by weakness of the knees and an uneasy sensation in the calves of the legs and soles of the feet.

I n the author’s experience these features were not observed in patients with signs of classical beriberi, but occurred occasionally in association with retrobulbar neuropathy and eighth nerve deafness, or in severe casea of “acute motor neuron myelinoclasis ”-the spastic syndrome (see Section VIII). They cannot, therefore, be properly regarded as resulting from thiamine deficiency and their etiology is more likely t o be closely linked with that of retrobulbar neuropathy and the cord syndromes.

Spillane and Scott (1945) described spinal ataxia and retrobulbar neuropathy in 23 German prisoners in the Middle East. Clarke and Sneddon (1946) observed the 40 ERIC K. CRUICKSHANK same combination in 31 prisoners and internees repatriated from HongKong. Spinal ataxia alone or in combination with retrobulbar neuropathy was not recognized in Changi Camp, Singapore, but some of the patients regarded as having signs of peripheral nerve damage may have in fact had spinal cord damage. Retrobulbar neuropathy and “neuritic beriberi ” were a rare combination.

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Advances in Research and Applications by Robert S.; Thimann, Kenneth V.; Marrian, G. F. Harris


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