Download e-book for kindle: Advances in the Treatment of Ischemic Stroke by M. Balestrino

By M. Balestrino

ISBN-10: 9535101366

ISBN-13: 9789535101369

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2009). Dynamic changes in cortical NADH fluorescence in rat focal ischemia: evaluation of the effects of hypothermia on propagation of peri-infarct depolarization by temporal and spatial analysis. Neurosci Lett. Vol. 449, No. 1, (January 2009), pp. , Binh, N. , & Hara, A. (2011). Galectin-3 expression in delayed neuronal death of hippocampal CA1 following transient forebrain ischemia, and its inhibition by hypothermia. Brain Research, Vol. 1382, (March 2011), pp. 266-74, ISSN 0006-8993 Scarabelli, T.

3. 1 The ischemic cascade The decrease in oxygen and glucose supply by the transient or permanent reduction of cerebral blood flow in cerebral ischemia triggers a series of excitotoxic, oxidative, inflammatory and apoptotic events known as the “ischemic cascade” which ends up in brain tissue death. Brain cells are dependent almost exclusively on oxygen and glucose supply for energy production through oxidative phosphorylation. The oxygen and glucose reduction causes accumulation of lactate increasing acidosis.

Molecular and Cellular Biology, Vol. 29, No. 1855-1868, ISSN 0270-7306 Baker, C. , Fiore, A. , Frazzini, V. , Choudhri, T. , Zubay, G. , & Solomon, R. A. (1995). Intraischemic hypothermia decreases the release of glutamate in the cores of 30 Advances in the Treatment of Ischemic Stroke permanent focal cerebral infarcts. Neurosurgery, Vol. 36, No. 5, (May 1995), pp. , & Cordoba, J. (2008). A 1H nuclear magnetic resonance-based metabonomic approach for grading hepatic encephalopathy and monitoring the effects of therapeutic hypothermia in rats.

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Advances in the Treatment of Ischemic Stroke by M. Balestrino


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